01 - If using meat, heat a skillet over medium heat and cook the ground beef or sausage, breaking it apart with a spoon, until fully browned. Drain off any excess fat and set aside.
02 - Place the cubed processed cheese and the entire can of diced tomatoes with green chilies (including the liquid) into a large saucepan or slow cooker.
03 - Stir in the cooked meat if using, along with the garlic powder and onion powder. Mix to combine evenly.
04 - Heat over medium-low, stirring frequently, until the cheese is completely melted and the mixture is smooth and creamy, approximately 8 to 10 minutes. Avoid boiling to prevent scorching.
05 - Transfer to a serving bowl or keep warm in a slow cooker on the warm setting. Serve hot with tortilla chips, crackers, or fresh vegetable sticks.