01 - Combine ground beef with salt, black pepper, garlic powder, and onion powder in a mixing bowl. Mix gently just until incorporated—overworking creates tough patties.
02 - Divide meat into 8 equal portions and shape into patties slightly wider than the slider buns, accounting for shrinkage during cooking.
03 - Heat grill or skillet over medium-high heat until properly hot for searing.
04 - Sear patties 2–3 minutes until browned, then flip. Place cheddar slice on each patty and cook 2–3 minutes more until cheese melts and patties reach desired doneness.
05 - Lightly toast slider buns on the grill or in a toaster until golden and warm.
06 - Spread condiments on toasted buns, layer lettuce, cheese-topped patty, tomato slices, pickles, and red onion. Crown with top bun and serve hot.